Calf and ankle injuries
Chargers’ RB Kalen Ballage, listed as questionable for Sunday with calf and ankle injuries, is not expected to play vs. the Bills, per source. It will leave the Chargers with RBs Austin Ekeler, Troymaine Pope and Josh Kelley. (Adam Schefter on Twitter)
Nerdy Football Analysis: This paves the way for Ekeler to receive the bulk of the running back work for the Chargers in a high-total game (52.5) against the Bills. Pope and Kelley will be available in supporting roles.