Quad injury
Todd Gurley is doubtful and Aqib Talib is out for Sunday’s game, Sean McVay said. (Lindsey Thiry on Twitter)
Nerdy Football Analysis: With Gurley out of the mix, Malcolm Brown and Darrell Henderson should handle all of the running back duties with Brown being the best fantasy play. The matchup is less than ideal with San Francisco giving up the second fewest fantasy points to the position including zero rushing touchdowns.